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The Genetics of DMD Neuromuscular disease basics Who can get DMD—how is it inherited? The gene that causes DMD is located on the X chromosome—and this means that boys are at greater risk of inheriting the disease. This is because boys don’t get a “backup copy” of the gene. Girls inherit two X chromosomes, one […]

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The Genetics of DMD Neuromuscular disease basics Understanding what drives the disease How do genes cause DMD? Damaged genes rob the body of a key protective protein DMD is caused by changes (mutations) in a certain gene, which in turn change the way the body works, leading to DMD. Genes are made up of DNA, […]

Overview 1

The Causes and Symptoms of Duchenne Muscular Dystrophy (DMD) Neuromuscular disease basics What is DMD? DMD is the most common and most severe form of muscular dystrophy. People with DMD can’t make a special protein called dystrophin, which acts as a shock absorber or stabilizer for muscles. Without dystrophin, muscle cells are easily damaged. If […]